Tetany secondary to phosphate enema toxicity, case report
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Keywords

Phosphate Enema
Constipation
Tetany
Hyperphosphemia
Hypocalcemia
Endocrinology 
Pharmacology
Calcium and Phosphate Metabolism
Adverse Drug Reaction
Functional Digestive Disorders

How to Cite

1.
Núñez Sánchez MJ, Leighton Swaneck S, Díaz F. Tetany secondary to phosphate enema toxicity, case report. Andes pediatr [Internet]. 2017 Jul. 27 [cited 2026 Apr. 15];88(3):383-7. Available from: https://andespediatrica.cl/index.php/rchped/article/view/283

Abstract

Background: Phosphate enemas are frequently used in the treatment of constipation. Errors in dosage and administration can lead to severe complications.

Objective: To report a case of severe toxicity of phosphate enemas in a child with no risk factors.

Case: 2 years old female, with functional constipation, was brought to emergency department because abdominal pain. She was diagnosed with fecal impaction and received half a bottle of Fleet Adult® (Laboratorio Synthon, Chile) two times, with no clinical resolution, deciding to start proctoclisis in pediatric ward. Soon after admission, she presented painful tetany, but alert and oriented.Patient was transferred to PICU where severe hyperphosphatemia and secondary hypocalcemia were confirmed. Her treatment included electrolyte correction; removal of residual phosphate enema and hyperhydration. Tetany resolved over 2 hours after admission and no other complications. Proctoclisis was performed and patient was discharged three days after admission with pharmacological management of constipation.

Conclusion:Phosphate enemas may cause serious complications in children with no risk factors. Errors in dosage, administration and removal of the enema are causes of toxicity in this group. Pediatricians and health personnel must be aware of risks and signs of toxicity of phosphate enema.

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