Cardiac Magnetic Resonance in long term follow-up of Tetralogy of Fallot
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Keywords

Tetralogy of Fallot
Pulmonary Regurgitation
End-Diastolic Volumes
Transannular Patch
Cardiac Magnetic Resonance
Cardiology 
Diagnostic Imaging
Congenital Heart Defects
Magnetic Resonance 

How to Cite

1.
Arancibia G. MF, Valderrama E. P, Urcelay M. G, Becker R. P, González F. R, Toro R. L, Parra R. R. Cardiac Magnetic Resonance in long term follow-up of Tetralogy of Fallot. Andes pediatr [Internet]. 2018 Jul. 5 [cited 2025 Oct. 22];89(3):361-7. Available from: https://andespediatrica.cl/index.php/rchped/article/view/536

Abstract

Introduction: Tetralogy of Fallot (TOF) is the most frequent cyanotic congenital heart disease. Pulmonary regurgitation (PR) and right ventricle (RV) enlargement and dysfunction are the most common long-term complications. Cardiac magnetic resonance (CMR) is the gold standard for RV evaluation.

Objective: To analyze CMR results in the follow-up of TOF patients.

Patients and Method: All CMR performed between 2007 and 2012 in TOF patients with transannular patch (TAP) repair or infundibular widening, and without pulmonary valve replacement (PVR) were included. Pulmonary regurgitant fraction (PRF), ventricular end-diastolic (EDV) and end-systolic volume (ESV), and ejection fraction (EF) were examined.

Results: 122 CMR were performed in 114 patients. Average age at CMR was 15.4±7.4 years. 53.3% of them presented severe PR (> 40%). RVEDV was 157.3 ± 38.6 ml/m2 , RVESV was 85.3 ± 27 ml/m2 and RVEF was 46.4 ± 7.1%. RVEDV was > 150 ml/ m2 in 48.4% and > 170 ml/m2 in 32.8% of patients. Patients with TAP showed larger RV volumes compared with those with infundibular widening. RVEDV > 170 ml/m2 showed worse RVEF that those with lower RVEDV (47.9 ± 7% vs 43.2 ± 6.4%, p < 0.01).

Conclusion: Almost half of the patients showed significant RV enlargement, demonstrating that the indication of CMR is late in their follow-up. TAP was associated with higher RVEDV and RVESV, but no worse RVEF.

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