Abstract
Introduction: Invasive Pneumococcal disease (IPD) is still a disease that is reported in Latin American countries.
Objetive: To describe the clinical characteristics, serotypes, and antibiotic susceptibility in patients with IPD in a pediatric hospital in Peru.
Material and Method: A descriptive and retrospective study was performed with data from patients under 18 years of age with IPD hospitalized between 2017 and 2020 at Instituto Nacional de Salud del Niño-Breña (Lima, Peru). Clinical variables, vaccination schedule, antibiotic susceptibility and isolated serotypes were described.
Results: 29 patients were included. The median age was 1.9 years (range 2 months to 8 years). 51.7% were female and the most frequent clinical form of IPD was bacteremia in 18 (62.1%) patients. 65.5% had the complete vaccination schedule. 82.8% of the germ isolation was from blood. Antibiotic resistance was more frequent to erythromycin 55.2% and penicillin 24.1%. The registered serotypes were 6C, 19A, 23A, and 24F. One patient died for meningitis.
Conclusions: IPD was more frequent from 1 to 5 years and in the clinical form of bacteremia. Five serotypes reported in previous studies with resistance to penicillin and erythromycin were found.
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