Vitamin D deficiency/insufficiency on healthy infants receiving standard supplementation
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Keywords

Vitamin D
Infants
Rickets
Dietary Supplements
Nutritional Sciences
Vitamins

How to Cite

1.
Bravo P, Navarro E, Mora M, Calvanese M, Taub M, Pérez D, Barros Ladrón de Guevara J, Guevara M, Pérez A, Canals A. Vitamin D deficiency/insufficiency on healthy infants receiving standard supplementation. Andes pediatr [Internet]. 2022 Feb. 14 [cited 2025 Oct. 24];93(1):59-64. Available from: https://andespediatrica.cl/index.php/rchped/article/view/3377

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Abstract

Vitamin D (VD) is essential for calcium and phosphorus metabolism. Its deficiency can cause rickets. In Chile, newborns receive 400UI/day supplementation from the first day of age until the first year. 

Objective: To describe the VD plasma levels in healthy infants who received supplementation and secondarily to correlate this with seasonality and nutritional status. 

Subjects and Method: Crosssectional study. Infants on exclusive or mixed breastfeeding, with monthly pediatric checkups recei- ving 400 UI VD supplementation were evaluated, measuring VD plasma levels at 6 months of age, weight, and length, and their nutritional status was classified according to the WHO growth referen- ces (weight/age and weight/length). The VD cut-off concentration values were ≤ 20 ng/ml, 21- 29 ng/ ml, and ≥ 30 ng/ml considered as deficiency, insufficiency, and sufficiency, respectively. 

Results: 40 infants were studied, 40% had insufficient levels and 40% presented deficiency. Season and nutritio- nal status were variables significantly related to lower VD values (Winter-Spring p = 0.007; at risk of malnutrition p = 0.038). 

Conclusions: The population who received supplementation presented a high frequency of VD deficiency and insufficiency which increases during winter and spring and in subjects at risk of malnutrition.

https://doi.org/10.32641/andespediatr.v93i1.3377
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