Abstract
Hepatoblastoma is the commonest malignant liver tumour in children. Complete surgical excision is required to achieve a cure.
Aim: An analysis of survival, clinical presentation, demography, adjuvent chemotherapy, surgical techniques, alphafoetoprotein levels and nutritional status in children with hepatoblastoma.
Patients and Method: 9 children were followed up between may 1997 and december 2000. Results: the mean age at diagnosis was 24 months, all had a palpable abdominal mass and elevated alphafoetoprotein levels. They received pre and postoperative chemotherapy. Surgical resections were accomplished with negative margins. There was no operative mortality. One patient relapsed after 9 months and died 6 months later, the 3 year DFS was 89%. The childrens weight returned to the normal percentiles after tumour resection.
Conclusions: A multidisciplinary team, early evaluation and specialized surgical approach are the basis for successful therapy in hepatoblastoma.
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Copyright (c) 2002 Revista Chilena de Pediatría